Chlorothiazide

Faʻamatalaga puʻupuʻu:

Igoa ole API Faailoga Faʻamatalaga US DMF  EU DMF  CEP
Chlorothiazide Diuretics USP / EP      

Oloa Faʻamatalaga

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FAʻAMATALAGA FAʻAMATALAGA

Talaʻaga

Chlorothiazide o se taofiofia o le carbonic anhydrase ma e laʻititi ifo le malosi nai lo le acetazolamide. O lenei lotoa ua faʻaalia e poloka reabsorption o sodium ma chloride ioni.

Faʻamatalaga

Chlorothiazide o se diuretic ma antihypertensive. (IC50 = 3.8 mM) Taunuʻuga: O isi Chlorothiazide sodium (Diuril) o se diuretic faʻaaogaina i totonu o le falemaʻi nofoaga poʻo mo oe lava faʻaaoga e pulea sili sua e fesoʻotaʻi ma le faʻatamaia o fatu fatu. E faʻaaogaina foi o se antihypertensive. Tele o taimi e ave ai i fualaʻau fualaʻau, e masani ona faia i le gutu faʻatasi pe faʻalua i le aso. I le tulaga o le ICU, o le chlorothiazide e avatua i le diurese o se tagata maʻi e faʻaopoopo i le furosemide (Lasix). Galue i se eseʻese auala nai lo furosemide, ma mitiia ulufale o se toe faʻamalolo lē tumau faʻatautaia faʻatonutonuina e ala i le nasogastric tube (NG tube), o fualaʻau e lua faʻamalosia le tasi ma le isi.

Tofotofoina le Falemai

Numera NCT Lagolago Tulaga Aso amata

Vaega

NCT03574857 Iunivesite o Virginia Faʻaletonu o le fatu | Faʻaletonu o le fatu Faʻatasi ma le faʻaititia o le vaevaeina o le vae | Maʻi o le fatu fatu | Faamai fatu Iuni 2018

Vaega 4

NCT02546583 Iunivesite a Yale | National Heart, Lung, ma le Blood Institute (NHLBI) Leai se fatu Aukuso 2015

E le agavaa ai

NCT02606253 Vanderbilt University | Vanderbilt University Medical Center Leai se fatu Fepuari 2016

Vaega 4

NCT00004360 Nofoaga Autu mo Suʻesuʻega Punaoa (NCRR) | Northwestern Iunivesite | Ofisa o Rare Faamaʻi (ORD) Maʻi suka Insipidus, Nefrogen Setema 1995

NCT00000484 National Heart, Lung, ma le Blood Institute (NHLBI) Faʻamaʻi Cardiovascular | Faamai ole fatu | Toto maualuga | Faʻamaʻi Vaskular Aperila 1966

Vaega 3

Fausaga o vailaʻau

Chlorothiazide

FAUTUAINA

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

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