Vericiguat

Fa'amatalaga Puupuu:

Igoa API Fa'ailoga Fa'afouga Aso e muta ai le pateni(US)
Vericiguat Gagana fatu Bayer ma MSD Mae.24, 2031


Fa'amatalaga Oloa

Faailoga o oloa

FAAMATALAGA O MEA FAI

Vericiguat o sepyrazolopyridineo lena lava5-fluoro-1H-pyrazolo[3,4-b]pyridinelea ua suia ai le amino hydrogen i le tulaga 1 e se vaega 2-fluorobenzyl ma lehydrogeni le tulaga 3 ua suia e le 4,6-diamino-5- [(methoxycarbonyl) amino] pyrimidin-2-yl vaega.E solubleguanylatecyclase stimulator lea e faʻaaogaina mo le togafitia o le faaletonu o le fatu.E i ai sana matafaioi o se solubleguanylatecyclase activator, o se vailaʻau vasodilator ma se vailaʻau faʻamaʻi toto.O seaminopyrimidine, apyrazolopyridine, o se ester carbamate ma se tuufaatasiga okenofluorine.

Vericiguat o loʻo suʻesuʻeina ile faʻataʻitaʻiga ile falemaʻi NCT02861534 (O se suʻesuʻega o le Vericiguat i tagata auai ma le faʻaletonu o le fatu ma le faʻaititia o le vaega o le ejection (HFrEF) (MK-1242-001)).

O Vericiguat o se SoluGuanylateCyclase Stimulator.Ole faiga ole gaioiga ole vericiguat ole aGuanylateCyclase Stimulator.

O le Vericiguat o se vaila'au e fa'aaogaina e pulea ma togafitia ai le faaletonu o le fatu i le fa'aitiitia o le vaega o le ejection (HFrEF).E aoga mo le fa'aletonu o le fatu fa'aleaga, fa'aletonu le fatu talu ai nei.Vericiguat e le fa'aumiumi le ola ae taofia le toe fa'afo'i.O lenei gaioiga o loʻo faʻamatalaina ai faʻamatalaga, faiga o gaioiga, fua, ma le faiga o le faʻatonuga a le vaega faʻapitoa, aʻafiaga leaga, faʻalavelave, ma le tele o faʻataʻitaʻiga e lagolago ai faʻamaoniga o le aoga o vailaʻau i le HFrEF.

PULEGA UIGA

Quality management1

Fautuaga18Poloketi Iloiloga Tulaga Tulaga Lelei ua fa'amaonia4, ma6o lo'o i lalo le faamaoniga.

Quality management2

A'oa'oga fa'ava-o-malo pulega lelei faiga ua faataatia faavae mautu mo le faatauina atu.

Quality management3

O le va'aiga lelei e fa'atautaia i le taamilosaga atoa o le olaga o le oloa ina ia mautinoa le lelei ma le togafitiga.

Quality management4

E lagolagoina e le vaega o Mataupu Tau Fa'apolofesa tulaga mana'omia ile taimi ole talosaga ma le resitalaina.

PULEGA O GALUEGA

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Potu Pulea DCS

PAAGA

Felagolagomai faavaomalo
International cooperation
Felagolagomai i totonu o aiga
Domestic cooperation

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