Abrocitinib
O le Abrocitinib o se gutu, mole laʻititi, Janus kinase (JAK) 1 inhibitor i le atinaʻeina mo togafitiga o tagata matutua ma tupulaga talavou e feololo ma ogaoga atopic dermatitis.
Abrocitinib o loʻo suʻesuʻeina ile suʻesuʻega ile falemaʻi NCT03796676 (JAK1 Inhibitor With Medicated Topical Therapy i Adolescents With Atopic Dermatitis).
Abrocitinib o loʻo atinaʻe nei e Pfizer mo togafitiga o le atopic dermatitis (eczema). Ose su'esu'ega tu'u gutu fa'atasi i aso ta'itasi Janus kinase 1 (JAK1) inhibitor.
Atopic dermatitis (AD) o se faʻamaʻi lavelave, faʻamaʻi, faʻamaʻi o le paʻu o loʻo faʻaalia i le maʻi, mageso tele, ma manua eczematous e aʻafia ai le tusa ma le 25% o tamaiti ma le 2% i le 3% o tagata matutua i le lalolagi atoa. Abrocitinib o se faʻaiʻuga filifilia o Janus kinase-1 (JAK1) enzyme e faʻalavelaveina ai le faʻalavelave. O le mea lea, matou te faʻamoemoe e iloilo le aoga ma le saogalemu o le abrocitinib mo AD feololo i le ogaoga AD.
Abrocitinib i le fua o le 100 mg poʻo le 200 mg o se vailaʻau aoga, faʻafeiloaʻi lelei, ma faʻamaonia i le togafitia o tagata mamaʻi i le atopic dermatitis e feololo i le ogaoga. Ae ui i lea, o le auʻiliʻiliga na fiafia i le aoga o le abrocitinib 200 mg i luga o le 100 mg, ae o aʻafiaga e pei o le nausea ma le ulu e ono tupu atili i le 200 mg.





Fautuaga18Poloketi Iloiloga Tulaga Tulaga Lelei ua fa'amaonia4, ma6galuega faatino o lo'o i lalo ole faamaoniga.

O faiga fa'ava-o-malo maualuga pulega lelei ua fa'ata'atia le fa'avae mautu mo fa'atauga.

O le va'aiga lelei e fa'atautaia i le taamilosaga atoa o le olaga o le oloa ina ia mautinoa le lelei ma le togafitiga.

E lagolagoina e le Vaega o Mataupu Tau Fa'apolofesa le tulaga lelei mana'omia ile taimi ole talosaga ma le resitalaina.


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